Product Description

PHARMACOLOGICAL ACTION:
ASPIRIN CARDIO **0 inhibits platelet aggregation by inactivation of platelet cyclo-oxygenase, the enzyme that produces the cyclic endoperoxide precursor of thromboxane A2.

INDICATIONS:
Indications related to inhibition of platelet aggregation: To reduce the risk of myocardial infarction in patients with unstable angina or in patients who have had a previous myocardial infarction. To reduce the risk of recurrent transient ischaemic attacks or stroke in men who have had transient ischaemia of the brain due to fibrin platelet emboli. To reduce the risk of graft occlusion following aortocoronary by-pass surgery.

CONTRA-INDICATIONS:
Patients with peptic or duodenal ulcers, haemophilia, thrombocytopenia or other bleeding tendencies,or intolerance (hypersensitivity) to aspirin or other salicylcates, severe renal impairment and patients receiving oral anti-coagulant therapy. Aspirin should not be taken during pregnancy and lactation, except under the advice and supervision of a medical doctor.

WARNING:
The optimal dose for inhibition of platelet aggregation in humans is not known. Do not use  ASPIRIN CARDIO **0 for indications related to the inhibition of platelet aggregation unless directed by a doctor. Aspirin has been implicated in Reyes Syndrome, a rare but serious illness in children and teenagers with chicken pox and influenza. A doctor should be consulted before use in such patients.

DOSAGE AND DIRECTIONS FOR USE:
Adults: **0 to **0 mg to be taken every day, preferably at the same time each day.
The tablets should be swallowed whole. Do not chew, break or crush the tablets as this will destroy the protective effect of the enteric coating.